Steven Kinsey, PhD (Affiliate)
I am an educator and researcher with specialized training in pain, chronic disease, immunology, and pharmacology. My lab uses interdisciplinary tools, including pharmacological and genetic experimental animal models, to study the opioid and endocannabinoid systems and how they control pain, inflammation, and the stress response. My goal, as principal investigator and mentor of a diverse team of graduate and undergraduate students, is to develop interventions to improve pain management and reduce human suffering.
Ph.D., Ohio State University, 2007
Trexler*, K.R., Eckard*, M.L., and Kinsey, S.G. (2019). CB1 positive allosteric modulation attenuates Δ9-THC withdrawal and NSAID-induced gastric inflammation. Pharmacology, Biochemistry, and Behavior. 177:27-33
Trexler*, R., Nass*, S.R., Crowe*, M.S., Jones**, M.S., McKitrick**, A.W., Gross, J., Siderovski, D.P., & Kinsey, S.G. (2018). Novel tests of spontaneous and precipitated THC withdrawal in mice. Drug and Alcohol Dependence. 191:14-24.
Neeley, B; Overholt**, T; Artz, E, Kinsey, SG, & Marsat, (2018). Selective and context-dependent social and behavioral effects of cannabinoids in Ghost Knifefish. Brain Behavior and Evolution. 91(4):214-227.
Crowe*, M.S., Wilson, C.D., Leishman, E., Banks, M., Bradshaw, H.B., Prather, P.L., & Kinsey, S.G. (2018). The monoacylglycerol lipase inhibitor KML29 synergistically potentiates the analgesic effects of gabapentin in mice. British Journal of Pharmacology. 174(23):4523-4539.
Donvito, G., Nass*, SR, Wilkerson, JL, Curry, Z., Schurman, LD, Kinsey, SG, & Lichtman, AH. (2018). The endogenous cannabinoid system: a budding source of targets for treating inflammatory and neuropathic pain. 43(1):52-79.
Crowe*, M.S. & Kinsey, S.G. (2017). MAGL inhibition modulates gastric secretion and motility following NSAID exposure in mice. European Journal of Pharmacology. 807:198-204.
Wilkerson, JL, Ghosh, S, Bagdas, D, Mason, BL, Crowe*, MS, Hsu, K, Wise, LE, Kinsey, SG, Damaj, MI, Cravatt, BF and Lichtman, AH. (2016). Diacylglycerol lipase beta inhibition reverses nociceptive behavior in mouse models of inflammatory and neuropathic pain. British Journal of Pharmacology. 173(10):1678-92.
McBean*, A.L., Kinsey, S.G., Montgomery-Downs, H.M. (2016). Effects of a Single Night of Postpartum Sleep on Childless Women’s Daytime Functioning. Physiology & Behavior. 156:137-47.
Ignatowska-Jankowska, B.M., Bailie, G., Crowe*, M.S., Kinsey, S.G., Ross, R., & Lichtman, A.H. (2015). A Cannabinoid CB1 Receptor Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with no Psychoactive Effects. 40(13):2948-59.
Ghosh, S., Kinsey, S.G., Liu, Q., Hruba, L, McMahon, L.R., Wise, L.E., Abdullah, R.A., Selley, D.E., Sim- Selley, L.J., Cravatt, B.F., & Lichtman, A.H. (2015). Full FAAH inhibition combined with partial monoacylglycerol lipase inhibition: Augmented and sustained antinociceptive effects with negligible cannabimimetic side effects in mice. Journal of Pharmacology and Experimental Therapeutics. 354:111-120.
Nass*, S.R., Long, J.Z., Schlosburg, J.E., Cravatt, B.F., Lichtman, A.H., & Kinsey, S.G. (2015) Endocannabinoid catabolic enzymes function to maintain thermal homeostasis in response to environmental or immunological challenge. Journal of Neuroimmune Pharmacology. 10:364-370.
Crowe*, M.S., Leishman, E., Gujjar, R., Mahadevan, A., Banks, M.L., Bradshaw, H.B., & Kinsey, S.G. (2015) Dual Cyclooxygenase and Monoacylglycerol Lipase Inhibition Synergistically Attenuates Neuropathic Pain. British Journal of Pharmacology. 172:1700-1712.
Grim, T.W., Ghosh, S., Hsu, K, Cravatt, B.F., Kinsey, S.G., & Lichtman, A.H. (2014). Co-administration of a FAAH inhibitor and an NSAID produces enhanced anti-allodynic effects in murine neuropathic and inflammatory pain models. Pharmacology, Biochemistry, and Behavior. 124:405-411.
Crowe*, M.S., Nass*, S.R., Gabella*, K.M., and Kinsey, S.G. (2014). The endocannabinoid system modulates stress, emotionality, and inflammation. Brain, Behavior, and Immunity. 42:1-5.
Schlosburg, JE, Kinsey, SG, Ignatowska-Jankowska, B, Ramesh, D, Abdullah, RA, Tao, Q, Booker, L, Long, JZ, Selley, DE, Cravatt, BF, and Lichtman, AH (2014). Prolonged monoacylglycerol lipase blockade causes equivalent CB1-receptor mediated adaptations in FAAH wild type and knockout mice. Journal of Pharmacology and Experimental Therapeutics. 350(2):196-204.
(*grad student mentee; **undergrad mentee)
|Mailing Address||231 Glenbrook Rd, U-4026, Storrs, CT, 06269, United States|