Savas Tasoglu, PhD
Assistant Professor, Mechanical Engineering (Affiliate)
I have worked on several global health and diagnostic projects during my Ph.D. and postdoctoral studies. We have recently developed a magnetic levitation-based device for real-time, label-free separation, as well as high-resolution monitoring of cell populations based on their unique magnetic and density signatures. This method allows studying a wide variety of cellular processes accompanied by transient or permanent changes in a cell’s fundamental characteristics as a biological material. As a senior author from my recently started lab at UConn, we have developed cell phone attachable, low-cost, label-free platform utilizing the principles of microfluidics and magnetic levitation, to diagnose sickle cell disease. In another project, we presented an inexpensive, rapid and portable microfluidic platform, which can streamline the process of an enzyme-linked immunosorbent assay (ELISA) in a fully automated manner for CD4 cell count. This is the first demonstration of capturing and detecting cells from unprocessed whole blood using the enzyme-linked immunosorbent assay (ELISA) in a microfluidic channel. Combined with cell phone imaging, this microfluidic ELISA platform holds great promise for offering rapid CD4 cell count to scale up much needed ART in resource-constrained settings. Our lab is interested in mainly developing low-cost and portable microfludic and magnetic approaches for health monitoring and disease diagnostics.
|Mailing Address||Department of Mechanical Engineering191 Auditorium RoadStorrs, CT 06269|
|Office Location||Room 372|