Mary Anne Amalaradjou

Associate Professor

PhD, DVM, MS

Animal Science


Research Interests

My research primarily focuses on food safety and gut health. Specifically, it is targeted towards understanding pathogen survival and persistence along the food chain, their virulence attributes and the application of probiotics to control foodborne pathogens. I also study the efficacy of currently applied intervention (hurdle) technologies to reduce pathogen transmission during pre- and post-harvest processing of fresh produce, meat, and dairy products. Beyond controlling pathogens in food systems my research investigates the potential application of probiotics and functional foods in the prevention and treatment of gut pathologies. Major efforts in my lab are directed towards elucidating the molecular cross-talk between diet, microbiome, and host on all levels of regulation, namely, genes, proteins and metabolites and developing evidence-based dietary interventions for restoring health and preventing chronic pathologies. Through all aspects of my research, my main objective is to improve food safety and promote public health. My research program has been funded by intramural (UConn Research Excellence Program and Storrs Agricultural Experimental Stations- USDA NIFA HATCH) and extramural funding agencies including the Center for Produce Safety, USDA, NSF, and the Foundation for Food and Agriculture.

Education

Ph.D., UConn, 2010
MS, UConn, 2009
MS, Indian Veterinary Research Institute, India, 2004
DVM, Pondicherry University, India, 2002

Recent Publications

1. Singh AK, Bai X, Amalaradjou MA, Bhunia AK. 2018. Antilisterial and antibiofilm activities of pediocin and LAP functionalized gold nanoparticles. Front. Sustain. Food Syst. 2, 74. https://doi.org/10.3389/fsufs.2018.00074

2. Mathew EN, Muyyarikkandy MS, Kuttappan D, Amalaradjou MA. 2018. Attachment of Salmonella enterica on mangoes and survival under conditions simulating commercial mango packing house and importer facility. Front Microbiol. 9, 1519. https://doi.org/10.3389/fmicb.2018.01519

3. Narayanan A, Nair MS, Muyyarikkandy M, Amalaradjou MA. 2018. Inhibition and inactivation of uropathogenic Escherichia coli biofilms on urinary catheters by sodium selenite. Int J Mol Sci. 19, 1073. http://www.mdpi.com/1422-0067/19/6/1703/pdf

4. Feng L, Muyyarikkandy MS, Brown SRB, Amalaradjou MA. 2018. Attachment and survival of Escherichia coli O157:H7 on in-shell hazelnuts. Int J Environ Res Public Health. 15, 1122. https://doi.org/10.3390/ijerph15061122.

5. Mathew EN, Muyyarikkandy MS, Bedell C, Amalaradjou MA. 2018. Efficacy of chlorine, chlorine dioxide and peroxyacetic acid in reducing Salmonella contamination in wash water and on mangoes under simulated mango packinghouse washing operations. Front Sustain Food Syst. 2, 18. https://doi.org/10.3389/fsufs.2018.00018.

6. Muyyarikkandy MS, Alqahtani FH, Mandoiu I, Amalaradjou MA. 2018. Draft genome sequence of Lactobacillus paracasei DUP 13076, which exhibits potent antipathogenic effects against Salmonella enterica serovars Enteritidis, Typhimurium, and Heidelberg. Genome announc. 6, e00065-18. https://doi.org/10.1128/genomeA.00065-18.

7. Muyyarikkandy MS, Alqahtani FH, Mandoiu I, Amalaradjou MA. 2018. Draft genome sequence of Lactobacillus rhamnosus NRRL B-442, a potential probiotic strain. Genome announc. 6, e00046-18. https://doi.org/10.1128/genomeA.00046-18.

8. Pattammattel A, Pande P, Kuttappan D, Puglia M, Basu AK, Amalaradjou MA, Kumar, CV. 2017. Controlling the graphene-bio interface: dispersions in animal sera for enhancing stability and reduced toxicity. Langmuir. 33, 14184-14194. https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.7b02854.

9. Muyyarikandy MS, Amalaradjou MA. 2017. Lactobacillus bulgaricus, Lactobacillus rhamnosus and Lactobacillus paracasei attenuate Salmonella Enteritidis, Salmonella Heidelberg and Salmonella Typhimurium colonization and virulence gene expression in vitro. Int J Mol Sci. 18, 2381. https://doi.org/10.3390/ijms18112381.

10. Narayanan A, Muyyarikkandy MS, Mooyottu S, Venkitanarayanan K, Amalaradjou MAR. 2017. Oral supplementation of trans-cinnamaldehyde reduces uropathogenic Escherichia coli colonization in a mouse model. Lett Appl Microbiol. 64, 192. https://doi.org/10.1111/lam.12713

11. Narayanan A, Surendran Nair M, Prasad, DK, Baskaran SA, Venkitanarayanan K, Amalaradjou MA. 2016. Inactivation of Acinetobacter baumannii biofilms on polystyrene, stainless steel and urinary catheters by octenidine dihydrochloride. Front Microbiol. 7, 847. https://doi.org/10.3389/fmicb.2016.00847.

12. Narayanan A, Baskaran SA, Amalaradjou MA, Venkitanarayanan K. 2015. Anticarcinogenic properties of medium chain fatty acids on human colorectal, skin and breast cells in vitro. Int J Mol Sci. 16, 5014-5027. https://doi.org/10.3390/ijms16035014.

13. Amalaradjou MA, Kim KS, Venkitanarayanan K. 2014. Sub-inhibitory concentrations of trans-cinnamaldehyde attenuate virulence in Cronobacter sakazakii in vitro. Int J Mol Sci. 15, 8639-8655. https://doi.org/10.3390/ijms15058639.

14. Amalaradjou MA, Venkitanarayanan, K. 2014. Antibiofilm effect of octenidine hydrochloride on Staphylococcus aureus, MRSA and VRSA. Pathogens. 3, 404-416. https://doi.org/10.3390/pathogens3020404.

15. Baskaran SA, Upadhyay A, Kollanoor-Johny A, Upadhyaya I, Mooyottu S, Amalaradjou MA, Schreiber D, Venkitanarayanan K. 2013. Efficacy of plant-derived antimicrobials as antimicrobial wash treatments for reducing enterohemorrhagic Escherichia coli O157:H7 on apples. J Food Sci. 78, M1399-1404. https://doi.org/10.1111/1750-3841.12174.

Contact Information
Emailmary_anne.amalaradjou@uconn.edu
Phone(860) 486-6620
Mailing Address17 Manter Road, Unit 4040, Storrs, CT, 06269, United States
CampusStorrs