Virgilio Lopez

Graduate Student, Kinesiology (Affiliate)


Research Overview

My research investigates the effects of exercise-induced stress on whole body and cellular physiology, incorporating animal models, human subjects, and a variety of bench-top and clinical techniques. As an InCHIP Graduate Student Fellow I will use the invertebrate model, Caenorhabditis elegans, to study effects of dehydration on muscle and neuronal gene expression, protein function, and aging. This model is especially powerful because C. elegans is ~40% genetically conserved in humans, allowing for parallels in gene expression, protein function, and aging to be drawn. Many similarities lie in the mechanisms of stress resistance, treatments that mitigate cellular damage or aging during stress, and drugs that effectively repair damage post-stress in C. elegans and humans. Therefore, I will also utilize laboratory and field-based studies to study the effects of dehydration on cardiovascular and kidney health, cognitive function and brain structure, and sport and functional performance in humans. At UConn I currently work on a number of projects that study hydration and gene expression in response to oxidative stress in exercise and sport performance. My work emphasizes a translational approach to studying physiological responses to exercise, utilizing techniques in molecular biology and applied genetics to answer complex research questions.

Education

Bachelor of Science, 2016, Molecular and Cell Biology, University of Connecticut

Contact Information
Emailvirgilio.lopez@uconn.edu
Mailing Address456 Tolland tpke
Apt 23B, Bldg 2
Willington, CT 06279